发明公开
EP1575506A2 METHODS FOR IMPROVEMENT OF LUNG FUNCTION USING TGF-BETA INHIBITORS
审中-公开
方法改善与TGF-β抑制剂肺功能
- 专利标题: METHODS FOR IMPROVEMENT OF LUNG FUNCTION USING TGF-BETA INHIBITORS
- 专利标题(中): 方法改善与TGF-β抑制剂肺功能
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申请号: EP03771821.0申请日: 2003-07-23
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公开(公告)号: EP1575506A2公开(公告)日: 2005-09-21
- 发明人: LI, Zhihe , LIU, David, Y. , MA, Jing, Ying , PROTTER, Andrew , SCHREINER, George, F. , TRAN, Thomas-Toan
- 申请人: Scios, Inc.
- 申请人地址: 6500 Paseo Padre Parkway Fremont, CA 94555 US
- 专利权人: Scios, Inc.
- 当前专利权人: Scios, Inc.
- 当前专利权人地址: 6500 Paseo Padre Parkway Fremont, CA 94555 US
- 代理机构: Denison, Christopher Marcus
- 优先权: US399369P 20020725
- 国际公布: WO2004010929 20040205
- 主分类号: A61K6/00
- IPC分类号: A61K6/00
摘要:
The invention concerns methods for improvement of lung function by administering non-peptide small molecule inhibitors of TGF-β specifically binding to the type I TGF-β receptor (TGFβ-R1). Preferably, the inhibitors are quinazoline derivatives.
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