发明公开
EP1598353A1 Pyrrolobenzimidazolones and their use as antiproliferative agents
审中-公开
吡咯并苯并咪唑酮和维生素A抗体增殖性Mittel
- 专利标题： Pyrrolobenzimidazolones and their use as antiproliferative agents
- 专利标题（中）： 吡咯并苯并咪唑酮和维生素A抗体增殖性Mittel
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申请号： EP04011703.8申请日： 2004-05-17
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公开(公告)号： EP1598353A1公开(公告)日： 2005-11-23
- 发明人: McConnel, Darryl , Steurer, Steffen , Krist, Bernd , Weyer-Czernilofsky, Ulrike , Impagnatiello, Maria , Treu, Matthias , Kauffmann-Hefner, Iris , Garin-Chesa, Pilar , Schnapp, Andreas
- 申请人： Boehringer Ingelheim International GmbH
- 申请人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 代理机构： Hammann, Heinz
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/4184
摘要：
The invention relates to pyrrolobenzimidazolone compounds of formula (I),
wherein A,T and R 1 to R 3 are defined as in claim 1, which possess tubulin inhibitory activity and are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation and the use thereof for preparing a pharmaceutical composition.
wherein A,T and R 1 to R 3 are defined as in claim 1, which possess tubulin inhibitory activity and are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation and the use thereof for preparing a pharmaceutical composition.
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