发明公开
EP1606317A2 ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION
无效
抗IL-22RA抗体和结合FOR USE启明创投与方法
- 专利标题： ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION
- 专利标题（中）： 抗IL-22RA抗体和结合FOR USE启明创投与方法
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申请号： EP04749427.3申请日： 2004-03-24
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公开(公告)号： EP1606317A2公开(公告)日： 2005-12-21
- 发明人: XU, Wenfeng , KINDSVOGEL, Wayne , CHANDRASEKHER, Yasmin, A. , DILLON, Stacey, R. , LEHNER, Joyce, M. , SIADAK, Anthony, W. , SIVAKUMAR, Pallavur, V. , MOORE, Margaret, D.
- 申请人： ZymoGenetics, Inc.
- 申请人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 当前专利权人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 代理机构： MacLean, Martin Robert
- 优先权： US457481P 20030324; US523295P 20031117
- 国际公布： WO2004085476 20041007
- 主分类号： C07K16/28
- IPC分类号： C07K16/28
摘要：
The present invention relates to blocking, inhibiting, reduceing, antagonizing or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 or both IL-20 and IL-22 using such antibodies and binding partners.
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