发明公开
EP1634073A2 PROCESSES FOR THE IDENTIFICATION OF MEDICAL TARGETS BY SCREENING AN ACTIVE AGENT FOR BINDING INTERACTIONS
审中-公开
一种用于识别靶向药物BY结合相互作用进行的审评的药物
- 专利标题： PROCESSES FOR THE IDENTIFICATION OF MEDICAL TARGETS BY SCREENING AN ACTIVE AGENT FOR BINDING INTERACTIONS
- 专利标题（中）： 一种用于识别靶向药物BY结合相互作用进行的审评的药物
-
申请号： EP04731591.6申请日： 2004-05-07
-
公开(公告)号： EP1634073A2公开(公告)日： 2006-03-15
- 发明人: SUPERTI-FUGA, Giulio , KRUSE, Ulrich , RYBIN, Vladimir , NEUBAUER, Gitte
- 申请人： CELLZOME AG
- 申请人地址： Meyerhofstrasse 1 69117 Heidelberg DE
- 专利权人： CELLZOME AG
- 当前专利权人： CELLZOME AG
- 当前专利权人地址： Meyerhofstrasse 1 69117 Heidelberg DE
- 代理机构： Huhn, Michael
- 优先权： EP03010290 20030507; US472663P 20030522
- 国际公布： WO2004099774 20041118
- 主分类号： G01N33/53
- IPC分类号： G01N33/53
摘要：
The present invention relates to a process for the isolation and identification of pharmaceutically relevant target compounds (TC) from a sample, said sample being derived from a living organism, wherein said target compound(s) bind(s) to a compound of interest (COI) under physiological conditions, said compound of interest (COI) being associated with a given impaired condition or disease. This process involves the isolation and the purification of the complex(es) formed by the compound. The present invention also relates to a process for the identification of a pharmaceutically effective compound useful for preventing and/or treating a given impaired condition or disease, wherein said compound is identified by its binding to a relevant target compound (TC) that has been identified and isolated according to the above mentioned process. Furthermore, the present application concerns a process for the identification of new uses (i.e. medical indications) of an active agent involving identifying diseases associated with the binding partner(s) of the active agent.
信息查询
IPC分类:
