发明公开
EP1639098A1 NON-INBRED EMBRYONIC STEM CELLS HAVING GOOD DEVELOPMENTAL POTENTIAL
审中-公开
不产生胚胎干细胞自交系发展潜力
- 专利标题: NON-INBRED EMBRYONIC STEM CELLS HAVING GOOD DEVELOPMENTAL POTENTIAL
- 专利标题(中): 不产生胚胎干细胞自交系发展潜力
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申请号: EP04737935.9申请日: 2004-07-08
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公开(公告)号: EP1639098A1公开(公告)日: 2006-03-29
- 发明人: Peterson, Alan Clarke
- 申请人: McGill University
- 申请人地址: 845 Sherbrooke Street West Montreal, Quebec H3A 2K7 CA
- 专利权人: McGill University
- 当前专利权人: McGill University
- 当前专利权人地址: 845 Sherbrooke Street West Montreal, Quebec H3A 2K7 CA
- 代理机构: Bentham, Andrew
- 优先权: US485430P 20030708
- 国际公布: WO2005005619 20050120
- 主分类号: C12N5/06
- IPC分类号: C12N5/06 ; A01K67/027
摘要:
The present invention provides non-inbred mouse embryonic stem (ES) cells comprising alleles derived from at least two different mouse strains and having high developmental potential. The ES cells optionally comprises a docking site for a transgene. Methods for production of the ES cells are also disclosed. This invention further provides chimeric and transgenic mice derived from the non-inbred ES cells and methods for deriving such mice.
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