公开(公告)号：EP1639098A1

公开(公告)日：2006-03-29

申请号：EP04737935.9

申请日：2004-07-08

申请人： McGill University

发明人： Peterson, Alan Clarke

IPC分类号： C12N5/06 ,  A01K67/027

CPC分类号： C12N15/873 ,  A01K67/027 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2267/0393 ,  C12N2517/00 ,  C12N2517/02

摘要： The present invention provides non-inbred mouse embryonic stem (ES) cells comprising alleles derived from at least two different mouse strains and having high developmental potential. The ES cells optionally comprises a docking site for a transgene. Methods for production of the ES cells are also disclosed. This invention further provides chimeric and transgenic mice derived from the non-inbred ES cells and methods for deriving such mice.