发明公开
EP1642234A1 METHOD AND APPARATUS FOR ANALYZING BIOLOGICAL TISSUES
审中-公开
VERFAHREN UND VORRICHTUNG ZUM ANALYSIEREN BIOLOGISCHER GEWEBE
- 专利标题: METHOD AND APPARATUS FOR ANALYZING BIOLOGICAL TISSUES
- 专利标题(中): VERFAHREN UND VORRICHTUNG ZUM ANALYSIEREN BIOLOGISCHER GEWEBE
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申请号: EP03817415.7申请日: 2003-07-09
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公开(公告)号: EP1642234A1公开(公告)日: 2006-04-05
- 发明人: DIOGUARDI, Nicola , GRIZZI, Fabio , RUSSO, Carlo , FRANCESCHINI, Barbara , VINCIGUERRA, Paolo , TORRES-MUNOZ, Ingrid
- 申请人: Humanitas Mirasole S.p.A. , Fondazione "Michele Rodriguez" - Istituto Scientifico per le Misure Quantitative in Medicina
- 申请人地址: Via Manzoni, 56 20089 Rozzano IT
- 专利权人: Humanitas Mirasole S.p.A.,Fondazione "Michele Rodriguez" - Istituto Scientifico per le Misure Quantitative in Medicina
- 当前专利权人: Humanitas Mirasole S.p.A.,Fondazione "Michele Rodriguez" - Istituto Scientifico per le Misure Quantitative in Medicina
- 当前专利权人地址: Via Manzoni, 56 20089 Rozzano IT
- 代理机构: Long, Giorgio
- 国际公布: WO2005006255 20050120
- 主分类号: G06T7/60
- IPC分类号: G06T7/60 ; G06T7/00
摘要:
The present invention relates to a method and an apparatus for processing images of irregularly shaped objects, such as biological specimens, in particular of human or animal origin, or images thereof. The metric quantification of a biological body part or tissue or of a material spot or aggregate of any origin, which is contained therein, is also performed by means of the invention method. In particular, the method of the present invention is applied to the 'confocal microscopy' technique. In particular, the present invention relates to a method of processing digital images comprising one or more objects to be quantified, the said method comprising the following main stages:- normalization of the digital images; - quantization of the images to one bit, further comprising at least one of the following stages: - calculating, from the said images quantized to one bit, the perimeter, area and/or fractal dimension of the said one or more objects to be quantified; - reconstructing, from the said images quantized to one bit, a 3D-image of the said one or more objects to be quantified, and/or- calculating, from the said normalized images, the fractal dimension of the overall image.
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