发明公开
- 专利标题： EIMERIA TENELLA ANTIGEN FOR IMMUNOTHERAPY OF COCCIDIOSIS
- 专利标题（中）： 柔嫩艾美耳球虫抗原球虫病免疫治疗
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申请号： EP04778551.4申请日： 2004-07-15
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公开(公告)号： EP1644408A1公开(公告)日： 2006-04-12
- 发明人: AYLSWORTH, Charles , JUDGE, John, W. , ROSENBURG, Barnett , HO, Siu-Cheong , JUCKETT, David , ZLATKIN, Igor, V. , ZLATKIN, Tatiana
- 申请人： Barros Research Institute , Michigan State University
- 申请人地址： 2430 College Road Holt, MI 48842 US
- 专利权人： Barros Research Institute,Michigan State University
- 当前专利权人： Barros Research Institute,Michigan State University
- 当前专利权人地址： 2430 College Road Holt, MI 48842 US
- 代理机构： Williams, Gareth Owen
- 优先权： US487336P 20030715
- 国际公布： WO2005010040 20050203
- 主分类号： C07K14/455
- IPC分类号： C07K14/455 ; A61K39/012
摘要：
The present invention provides compositions and methods for the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases, for stimulating an immune response in a subject, and for use as an alternative to interleukin-12 (IL-12) treatment. In particular, the present invention provides Apicomplexa-related proteins (ARPs) that have immune stimulatory activity and thus have uses in the treatment and prevention of cancer and infectious diseases and in immune modulation. Compositions comprising an ARP are provided. Methods of use of an ARP for the prevention and/or treatment of cancer and/or infectious diseases, for use as an alternative to interleukin-12 (IL-12) treatment, and for eliciting an immune response in a subject, are also provided.
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