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    DNA encoding an antigenic protein of eimeria apical membrane antigen 1 and use thereof
    2.
    发明公开
    DNA encoding an antigenic protein of eimeria apical membrane antigen 1 and use thereof 有权
    Kodierende DNSfürein Eimeria Apical Membran Antigen 1 und dessen Verwendungen

    公开(公告)号：EP1666489A1

    公开(公告)日：2006-06-07

    申请号：EP05257384.7

    申请日：2005-11-30

    申请人： ZEON CORPORATION

    发明人： Sato, Takanori, Zeon Corporation

    IPC分类号： C07K14/455 ,  A61K39/012 ,  A61K48/00 ,  C12N15/00 ,  A61K33/02

    CPC分类号： C07K14/455 ,  A61K39/00

    摘要： This invention provides a novel DNA for preventing avian coccidiosis and use thereof. The novel DNA encodes an antigenic protein of Eimeria apical membrane antigen 1, and is used for DNA vaccine and/or for vaccine comprising the recombinant protein deduced from the said DNA sequence as a main ingredient. The chickens immunized with vaccines described herein can be induced immunity against coccidiosis.

    摘要翻译： 本发明提供了用于预防禽类球虫病的新型DNA及其应用。 该新型DNA编码艾美球虫顶端膜抗原1的抗原性蛋白，用于DNA疫苗和/或包含以所述DNA序列推导的重组蛋白为主要成分的疫苗。 用本文所述的疫苗免疫的鸡可以诱导针对球虫病的免疫。

    Eimeria hydrophilic polypeptides as vaccines
    5.
    发明公开
    Eimeria hydrophilic polypeptides as vaccines 审中-公开
    艾美球虫亲水多肽，我在Verstenden的Verwendung

    公开(公告)号：EP1731611A2

    公开(公告)日：2006-12-13

    申请号：EP06116119.6

    申请日：1999-10-01

    申请人： Intervet International BV

    发明人： Schaap, Theodorus Cornelis ,  Kuiper, Catharina Maria ,  Vermeulen, Arnoldus Nicolaas

    IPC分类号： C12N15/30 ,  C07K14/455 ,  C12N1/21 ,  C07K16/20 ,  A61K39/12 ,  C12Q1/68 ,  A61K39/012

    CPC分类号： C07K14/455 ,  A61K39/00

    摘要： The present invention relates to hydrophilic Eimeria polypeptides, DNA-fragments encoding those peptides, recombinant DNA molecules comprising such DNA-fragments, live recombinant carriers comprising such DNA-fragments or recombinant DNA molecules and host cells comprising such DNA-fragments, recombinant DNA molecules or live recombinant carriers. Furthermore, the invention relates to antibodies against the polypeptides and to coccidiosis vaccines based upon said polypeptides. The invention also relates to methods for the preparation of such antibodies and vaccines, and to methods for the detection of Eimeria parasites and antibodies against Eimeria parasites.

    摘要翻译： 本发明涉及亲水艾美球虫多肽，编码这些肽的DNA片段，包含此类DNA片段的重组DNA分子，包含该DNA片段或重组DNA分子的活重组载体和包含该DNA片段的宿主细胞，重组DNA分子或 活重组载体。 此外，本发明涉及基于所述多肽的针对多肽的抗体和针对球虫病的疫苗。 本发明还涉及制备这种抗体和疫苗的方法，以及用于检测艾美虫寄生虫和抗艾美球虫寄生虫抗体的方法。

    IFI206, A NOVEL INTERFERON-INDUCED POLYPEPTIDE, AND NUCLEIC ACIDS ENCODING THE SAME
    7.
    发明公开
    IFI206, A NOVEL INTERFERON-INDUCED POLYPEPTIDE, AND NUCLEIC ACIDS ENCODING THE SAME 审中-公开
    IFI206，小说，干扰素诱导多肽，为此编码核酸

    公开(公告)号：EP1282696A1

    公开(公告)日：2003-02-12

    申请号：EP01918720.2

    申请日：2001-03-13

    申请人： Curagen Corporation ,  GENENTECH, INC.

    发明人： LEWIN, David, A. ,  ADAMS, Sean

    IPC分类号： C12N15/00 ,  C12N15/12 ,  C12N15/20 ,  C07K14/435 ,  C07K14/455 ,  A61K38/17 ,  A61K38/21

    摘要： The present invention provides novel mouse interferon-inducible proteins (IFI206 and naturally occuring variants) modulated under conditions that affect metabolic status and the polynucleotides that identify and encode IFI206. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding IFI206 and for a method for producing the protein. The invention also provides pharmaceutical compositions containing IFI206 and the use of such compositions for the prevention or treatment of diseases associated with the expression of IFI206. Additionally, the invention provides antisense molecules to IFI206 and their use in the treatment of diseases associated with the expression of IFI206. The invention also provides diagnostic assays that utilize polynucleotides that hybridize with naturally occurring sequences encoding IFI206 and antibodies that specifically bind to the protein.