发明授权
- 专利标题: BRANCHED CARBOXYLIC ACID COMPOUND AND USE THEREOF
- 专利标题(中): 支化羧酸化合物及其用途
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申请号: EP04747782.3申请日: 2004-07-14
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公开(公告)号: EP1650182B1公开(公告)日: 2009-10-07
- 发明人: IMAWAKA, Haruo c/o Ono Pharmaceutical Co., Ltd. , HASEGAWA, Tomoyuki c/o Ono Pharm. Co., Ltd. , SAKUYAMA, Shigeru c/o Ono Pharm. Co., Ltd. , KAWANAKA, Yasufumi c/o Ono Pharm. Co., Ltd. , AKIYAMA, Tsutomu c/o Ono Pharmaceutical Co., Ltd. , HOSHIKAWA, Masamitsu c/o Ono Pharm. Co., Ltd. , MATSUDA, Saiko c/o Ono Pharmaceutical Co., Ltd.
- 申请人: ONO PHARMACEUTICAL CO., LTD.
- 申请人地址: 1-5, Doshomachi 2-chome Chuo-ku Osaka-shi, Osaka 541-8526 JP
- 专利权人: ONO PHARMACEUTICAL CO., LTD.
- 当前专利权人: ONO PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: 1-5, Doshomachi 2-chome Chuo-ku Osaka-shi, Osaka 541-8526 JP
- 代理机构: Henkel, Feiler & Hänzel
- 优先权: JP2003274988 20030715
- 国际公布: WO2005005366 20050120
- 主分类号: C07C55/02
- IPC分类号: C07C55/02 ; C07C59/01 ; C07C59/185 ; A61K31/19 ; A61K31/194 ; A61K31/366 ; A61K45/00 ; A61P25/00 ; A61P25/14 ; A61P25/16 ; A61P25/28
摘要:
A compound represented by the general formula (I): (wherein R represents optionally protected hydroxy or oxo; indicates alpha configuration, beta configuration, or a mixture of these in an arbitrary proportion; n is an integer of 1 to 3; and m is an integer of 0 to 10, provided that two or more R 's are not bonded to the same carbon atom other than the terminal carbon atoms), a salt of the compound, or a prodrug of either. The compound represented by the general formula (I) is effective in, e.g., improving the function of astrocytes. It is useful as a preventive and/or therapeutic agent for brain infarction or nerve function disorders after brain infarction and for neurodegenerative diseases such as Parkinson's disease, Parkinson's syndrome, amyotrophic lateral sclerosis, and Alzheimer's disease.
公开/授权文献
- EP1650182A1 BRANCHED CARBOXYLIC ACID COMPOUND AND USE THEREOF 公开/授权日:2006-04-26
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