发明公开
- 专利标题： CANCER METASTASIS INHIBITOR
- 专利标题（中）： KREBSMETASTASENHEMMER
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申请号： EP04772286.3申请日： 2004-08-20
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公开(公告)号： EP1661582A1公开(公告)日： 2006-05-31
- 发明人: OCHIAI, Atsushi , SHITARA, Kenya; c/o BioFrontier Laboratories , NAKAMURA, Kazuyasu; c/oBioFrontier Laboratories , OHKI, Yuji; c/o Tokyo Research Laboratories, Kyowa
- 申请人： KYOWA HAKKO KOGYO CO., LTD. , JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER
- 申请人地址： 6-1, Ohtemachi 1-chome Chiyoda-ku, Tokyo 100-8185 JP
- 专利权人： KYOWA HAKKO KOGYO CO., LTD.,JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER
- 当前专利权人： KYOWA HAKKO KOGYO CO., LTD.,JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER
- 当前专利权人地址： 6-1, Ohtemachi 1-chome Chiyoda-ku, Tokyo 100-8185 JP
- 代理机构： Vossius & Partner
- 优先权： JP2003297871 20030821; JP2004139707 20040510
- 国际公布： WO2005018671 20050303
- 主分类号： A61K45/00
- IPC分类号： A61K45/00 ; A61K39/395 ; A61P35/00
摘要：
An object of the present invention is to provide a cancer metastasis inhibitor or, more particularly, a useful pharmaceutical composition for treating of bone metastasis and liver metastasis.
In accordance with the invention, a cancer metastasis inhibitor comprising a substance inhibiting the activity of IGF (insulin-like growth factor)-I and IGF-II is an active ingredient is provided. The inhibitor can significantly suppress the metastasis of cancer.
In accordance with the invention, a cancer metastasis inhibitor comprising a substance inhibiting the activity of IGF (insulin-like growth factor)-I and IGF-II is an active ingredient is provided. The inhibitor can significantly suppress the metastasis of cancer.
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