公开(公告)号：EP1661582A1

公开(公告)日：2006-05-31

申请号：EP04772286.3

申请日：2004-08-20

申请人： KYOWA HAKKO KOGYO CO., LTD. ,  JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER

发明人： OCHIAI, Atsushi ,  SHITARA, Kenya; c/o BioFrontier Laboratories ,  NAKAMURA, Kazuyasu; c/oBioFrontier Laboratories ,  OHKI, Yuji; c/o Tokyo Research Laboratories, Kyowa

IPC分类号： A61K45/00 ,  A61K39/395 ,  A61P35/00

CPC分类号： A61K31/00

摘要： An object of the present invention is to provide a cancer metastasis inhibitor or, more particularly, a useful pharmaceutical composition for treating of bone metastasis and liver metastasis.
In accordance with the invention, a cancer metastasis inhibitor comprising a substance inhibiting the activity of IGF (insulin-like growth factor)-I and IGF-II is an active ingredient is provided. The inhibitor can significantly suppress the metastasis of cancer.

摘要翻译： 本发明的目的是提供一种癌症转移抑制剂，更具体地，提供一种治疗骨转移和肝转移的有用的药物组合物。 根据本发明，提供了包含抑制IGF（胰岛素样生长因子）-I和IGF-II的活性的物质的癌症转移抑制剂是活性成分。 抑制剂可显着抑制癌症转移。