发明公开
- 专利标题: CANCER TREATMENT WITH EPOTHILONES
- 专利标题(中): 用乙氧基化物治疗癌症
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申请号: EP04764699.7申请日: 2004-09-01
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公开(公告)号: EP1663214A1公开(公告)日: 2006-06-07
- 发明人: DILEA, Clifford , MCSHEEHY, Paul, M. J. , MAIRA, Sauveur-Michel , TANAKA, Chiaki , WARTMANN, Markus
- 申请人: Novartis AG , Novartis Pharma GmbH
- 申请人地址: Lichtstrasse 35 4056 Basel CH
- 专利权人: Novartis AG,Novartis Pharma GmbH
- 当前专利权人: Novartis AG,Novartis Pharma GmbH
- 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
- 代理机构: Liphardt, Bernd
- 优先权: US499548P 20030902
- 国际公布: WO2005020989 20050310
- 主分类号: A61K31/426
- IPC分类号: A61K31/426 ; A61K31/427 ; A61K45/06 ; A61P35/00
摘要:
The present invention relates to an in vivo regimen for the treatment of a proliferative disease, preferably a tumor that is refractory to treatment with one or more chemotherapeutics other than a epothilone, where an epothilone is administered in a loading dose followed by at least 1 maintenance dose.
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