发明公开
EP1666048A2 METHOD FOR PRODUCING INSULIN FROM A NATURAL SOURCE AND INSULIN
审中-公开
维多利亚ZUR HERSTELLUNG肛门胰岛素AUS EINERNATÜRLICHENQUELLE UND INSULIN
- 专利标题： METHOD FOR PRODUCING INSULIN FROM A NATURAL SOURCE AND INSULIN
- 专利标题（中）： 维多利亚ZUR HERSTELLUNG肛门胰岛素AUS EINERNATÜRLICHENQUELLE UND INSULIN
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申请号： EP04788526.4申请日： 2004-09-17
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公开(公告)号： EP1666048A2公开(公告)日： 2006-06-07
- 发明人: Tsygankov, Vladimir Vladimirovich
- 申请人： Tsygankov, Vladimir Vladimirovich
- 申请人地址： ul. Lilyakova, 72, Khvastovichi Kaluzhskaya obl., 577298 RU
- 专利权人： Tsygankov, Vladimir Vladimirovich
- 当前专利权人： Tsygankov, Vladimir Vladimirovich
- 当前专利权人地址： ul. Lilyakova, 72, Khvastovichi Kaluzhskaya obl., 577298 RU
- 代理机构： Dunne, Emma Louise
- 优先权： RU2003127995 20030918
- 国际公布： WO2005026315 20050324
- 主分类号： A61K35/39
- IPC分类号： A61K35/39 ; A61K38/28 ; A61P3/10 ; C07K14/625
摘要：
The inventive method for producing insulin consists in using a reindeer pancreas which is homogenized in an ethanol hydrochloride solution, whereupon extraction is effected followed by clarifying the solution to obtain a supernatant fluid which is subjected to an ion-exchange chromatography and isoelectric precipitation to produce insulin as the desired product which is purified by a high-efficiency reversed-phase liquid co-chromatography. The resultant insulin is capable of competing for a bond with an insulin receptor at a concentration over 100 ng/ml.
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