发明公开
EP1666476A1 A process for purification of proanthocyanidin oligomers
有权
Verfahren zur Reinigung von Proanthocyanidin-Oligomeren
- 专利标题： A process for purification of proanthocyanidin oligomers
- 专利标题（中）： Verfahren zur Reinigung von Proanthocyanidin-Oligomeren
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申请号： EP05024213.0申请日： 2000-03-03
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公开(公告)号： EP1666476A1公开(公告)日： 2006-06-07
- 发明人: Honda, Shinkichi , Takahashi, Tomoya c/o Kyowa Hakko Kogyo Co.,Ltd. , Kamimura, Ayako c/o Kyowa Hakko Kogyo Co.,Ltd. , Matsuoka, Takako , Kanda, Tomomasa , Yanagida, Akio , Hieda, Kazuo
- 申请人： KYOWA HAKKO KOGYO CO., LTD. , THE NIKKA WHISKY DISTILLING CO., LTD.
- 申请人地址： 6-1, Ohtemachi 1-chome Chiyoda-ku, Tokyo 100-8185 JP
- 专利权人： KYOWA HAKKO KOGYO CO., LTD.,THE NIKKA WHISKY DISTILLING CO., LTD.
- 当前专利权人： KYOWA HAKKO KOGYO CO., LTD.,THE NIKKA WHISKY DISTILLING CO., LTD.
- 当前专利权人地址： 6-1, Ohtemachi 1-chome Chiyoda-ku, Tokyo 100-8185 JP
- 代理机构： Vossius & Partner
- 优先权： JP11638099 19990423
- 主分类号： C07D311/60
- IPC分类号： C07D311/60 ; C07D311/62 ; C12P17/06
摘要：
The present invention relates to a process for purifying dimeric to pentameric proanthocyanidin oligomers with a uniform polymerization degree which comprises separating and purifying the proanthocyanidin oligomers by polymerization degree from raw materials containing the proanthocyanidin oligomers or crude purification products therefrom by normal phase silica gel liquid chromatography using as a mobile phase a single solvent or a mixed solvent of two or more solvents selected from the group consisting of an ester solvent, a ketone solvent, a hydrocarbon solvent, an ether solvent and an alcohol solvent.
公开/授权文献
- EP1666476B1 A process for purification of proanthocyanidin oligomers 公开/授权日：2008-01-16
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