发明公开
EP1670791A2 THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF
审中-公开
与使用的ATP酶抗炎效果和组合物以及噻吩类化合物及其用途
- 专利标题: THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF
- 专利标题(中): 与使用的ATP酶抗炎效果和组合物以及噻吩类化合物及其用途
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申请号: EP04794006.9申请日: 2004-10-01
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公开(公告)号: EP1670791A2公开(公告)日: 2006-06-21
- 发明人: HODGE, Carl, Nicholas , JANZEN, William, P. , WILLIAMS, Kevin, Peter , CHEATHAM, Lynn, A.
- 申请人: Amphora Discovery Corporation
- 申请人地址: 800-4 Capitola Drive Durham, NC 27713 US
- 专利权人: Amphora Discovery Corporation
- 当前专利权人: Amphora Discovery Corporation
- 当前专利权人地址: 800-4 Capitola Drive Durham, NC 27713 US
- 代理机构: Marshall, Cameron John
- 优先权: US508393P 20031003
- 国际公布: WO2005033102 20050414
- 主分类号: C07D409/12
- IPC分类号: C07D409/12 ; A61K31/381 ; A61P35/00 ; C07D333/40 ; C07D333/38 ; A61K31/33 ; A61P25/28 ; C07D413/12 ; C07D333/68 ; C07D487/04 ; A61P29/00 ; A61P3/10 ; C07D471/04 ; C07D495/04 ; C07D409/14 ; C07D417/12 ; C07D495/18 ; C07D409/04 ; C07D333/36 ; C07D513/04
摘要:
Thiophene-based compounds of formula (I) exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed. These compounds are useful in the treatment of Alzheimer’s disease, stroke, diabetes, obesity, inflammation and cancer.
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