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公开(公告)号:EP4460283A1
公开(公告)日:2024-11-13
申请号:EP23702387.4
申请日:2023-01-06
申请人: V. Mane Fils
发明人: GRASSET, Fabien
IPC分类号: A61K8/34 , A61K8/49 , A61Q13/00 , C07C13/18 , C07C13/19 , C07C55/02 , C07C61/00 , C07C321/20 , C07D319/08 , C07D333/22 , C07D409/04 , A61Q19/00
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公开(公告)号:EP4149620B1
公开(公告)日:2024-10-23
申请号:EP21730365.0
申请日:2021-05-12
发明人: KOCH, Kevin , HUNT, Kevin , SCHLACHTER, Stephen , RUSSELL, Alan
IPC分类号: A61P21/00 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , A61K31/501
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公开(公告)号:EP4446315A1
公开(公告)日:2024-10-16
申请号:EP23831788.7
申请日:2023-06-20
申请人: LG Chem, Ltd.
发明人: KIM, Seonwoo , HA, Jae Seung , GEUM, Sujeong , CHO, Woo Jin , CHA, Yongbum , HWANG, Sunghyun , LEE, Woochul
IPC分类号: C07D307/92 , C07D493/04 , C07D407/10 , C07D413/10 , C07D407/04 , C07D409/10 , C07D409/04 , H10K85/60
摘要: The present specification relates to a compound of Chemical Formula 1 and an organic light emitting device including the same.
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4.
公开(公告)号:EP4433161A1
公开(公告)日:2024-09-25
申请号:EP22818686.2
申请日:2022-11-17
申请人: Samsara Therapeutics Inc. , Institut National de la Santé et de la Recherche Médicale (INSERM) , Université de Paris Cité , Sorbonne Université
发明人: HAMLEY, Peter , GALLOWAY, Warren , KEPP, Oliver , KROEMER, Guido
IPC分类号: A61P9/00 , A61P25/08 , A61P25/28 , A61P29/00 , A61P31/00 , A61P35/00 , A61P43/00 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/04 , C07D409/14 , C07D417/04 , C07D417/14 , A61K31/426 , A61K31/454 , A61K31/4155
CPC分类号: C07D417/14 , C07D401/14 , C07D417/04 , C07D409/14 , C07D409/04 , C07D405/14 , C07D403/04 , C07D403/14 , A61P25/28 , A61P35/00 , A61P25/08 , A61P31/00 , A61P9/00 , A61P29/00 , A61P43/00
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公开(公告)号:EP4424671A1
公开(公告)日:2024-09-04
申请号:EP22887535.7
申请日:2022-10-24
申请人: Huchembio Co., Ltd.
发明人: LEE, Sang Hak , YOON, Mi Ja , KIM, Mi Sun , LEE, Do Hyung , KANG, Seung Hee
IPC分类号: C07D217/02 , A61K31/472 , A61K31/4725 , A61K31/4985 , A61K31/517 , A61K31/4375 , A61K31/437 , A23L33/10 , C07D405/04 , C07D409/04
CPC分类号: A23L33/10 , A61K31/437 , A61K31/4375 , A61K31/472 , A61K31/4725 , A61K31/4985 , A61K31/517 , C07D217/02 , C07D409/04 , C07D405/04
摘要: The present invention relates to a novel tricyclic derivative compound or a pharmaceutically acceptable salt thereof and a use thereof, in which it has excellent STAT3 inhibitory activity and was found to exhibit an excellent inhibitory effect compared to known compounds in phase-3 clinical trials, and thus can be used as a therapeutic agent for STAT3 related diseases.
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6.
公开(公告)号:EP3598515B1
公开(公告)日:2024-09-04
申请号:EP18184297.2
申请日:2018-07-18
IPC分类号: C07D221/18 , C07D239/26 , C07D251/24 , C07D403/10 , C07D239/70 , C07D405/04 , C07F9/53 , C07F9/6521 , C07D409/04 , C07D401/10 , H10K85/60
CPC分类号: C07D221/18 , C07D239/26 , C07D239/70 , C07D251/24 , C07D401/10 , C07D403/10 , C07D405/04 , C07D409/04 , C07F9/5325 , C07F9/6521 , Y02E10/549 , H10K85/615 , H10K85/654
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7.
公开(公告)号:EP3917908B1
公开(公告)日:2024-08-14
申请号:EP20747897.5
申请日:2020-01-27
IPC分类号: C07D231/12 , C07D409/04 , B01J19/00
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公开(公告)号:EP4225736B1
公开(公告)日:2024-07-24
申请号:EP21786502.1
申请日:2021-10-08
IPC分类号: C07D213/70 , C07D213/79 , C07D213/81 , C07D213/84 , C07D409/04
CPC分类号: C07D213/79 , C07D213/81 , C07D213/84 , C07D213/70 , C07D409/04
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公开(公告)号:EP3994113B1
公开(公告)日:2024-07-03
申请号:EP20742680.0
申请日:2020-07-14
IPC分类号: C07F15/04 , C07B37/04 , C07B43/04 , C07D217/24 , C07D409/04 , C07D213/12 , C07D209/12 , C07D295/073 , C07D311/60 , B01J31/18 , B01J31/22 , B01J31/24
CPC分类号: C07F15/04 , C07B43/04 , C07D217/24 , C07D409/04 , C07B37/04 , C07D213/12 , C07D295/073 , C07D311/60 , C07D209/12 , B01J31/2291 , B01J2231/42520130101 , B01J31/2404 , B01J2540/22520130101 , B01J2231/32320130101 , B01J2231/6420130101 , B01J2540/2220130101 , B01J2231/5220130101 , B01J31/182 , B01J2231/426120130101 , B01J2231/421620130101 , B01J2531/84720130101 , B01J2231/2020130101 , B01J31/2457 , B01J2231/424420130101 , B01J2231/4920130101 , B01J31/1815 , B01J31/2409 , B01J2231/428320130101 , B01J2531/020520130101 , B01J2531/84220130101 , B01J31/2273 , B01J2231/32620130101 , B01J2231/421120130101
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公开(公告)号:EP4389738A1
公开(公告)日:2024-06-26
申请号:EP22858734.1
申请日:2022-08-17
发明人: YU, Ha Na , SHIN, Young Sook , PARK, Dohyun , YOON, Kyeong Jin , LIM, Sang Kyun , KIM, Donggeon , KI, Dong Hyuk , KIM, Eun-Jung , NAM, Joonwoo , HAN, Wooseok , YU, Jihyun , KIM, Ji Eun
IPC分类号: C07D237/14 , A61K31/50 , A61P35/00 , C07D405/04 , C07D401/04 , C07D409/04
摘要: There is provided a novel compound of Formula I and a use thereof for the prevention or treatment of a disease associated with SOS1. In one aspect of the present invention, the novel compound is useful for the prevention or treatment of a SOS1 mediated disease such as cancer and RASopathy by inhibiting the interaction between SOS1 and RAS family proteins or between SOS1 and RAC1.
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