发明公开
EP1671655A1 GENE THERAPY FOR SKIN DISEASES USING NEEDLE FREE SYRINGE
审中-公开
GENTHERAPIEFÜRHAUTERKRANKUNGEN MIT NADELFREIER SPRITZE
- 专利标题： GENE THERAPY FOR SKIN DISEASES USING NEEDLE FREE SYRINGE
- 专利标题（中）： GENTHERAPIEFÜRHAUTERKRANKUNGEN MIT NADELFREIER SPRITZE
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申请号： EP04772726.8申请日： 2004-08-27
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公开(公告)号： EP1671655A1公开(公告)日： 2006-06-21
- 发明人: KUNUGIZA, Yasuo , TOMITA, Naruya , YOSHIKAWA, Hideki , TANIYAMA, Yoshiaki , TAMAI, Katsuto , MORISHITA, Ryuichi
- 申请人： AnGes MG, Inc.
- 申请人地址： 7-7-15 Saito-Asagi Ibaraki-shi, Osaka 567-0085 JP
- 专利权人： AnGes MG, Inc.
- 当前专利权人： AnGes MG, Inc.
- 当前专利权人地址： 7-7-15 Saito-Asagi Ibaraki-shi, Osaka 567-0085 JP
- 代理机构： Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
- 优先权： JP2003307713 20030829
- 国际公布： WO2005021045 20050310
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K38/16 ; A61K31/7088 ; A61P17/00 ; A61P17/02 ; A61P17/06 ; A61K9/08
摘要：
The present invention provides highly useful clinical methods for treating skin disorders, particularly intractable skin disorders. Specifically, the methods comprise injecting/subcutaneously introducing a 10 µg to 10 mg dose of a polynucleotide, such as a DNA, oligonucleotide, RNA, siRNA, and antisense, around a lesion associated with a skin disorder, such as a wound, cutaneous ulcer, or psoriasis, using a needleless syringe that injects a pharmaceutical liquid by using gas pressure or the elastic force of an elastic member to drive a piston.
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