发明授权
EP1678172B1 AZABICYCLIC COMPOUNDS FOR RELIEVING PAIN AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS
有权
氮杂双环化合物缓解疼痛和中枢神经系统疾病的治疗
- 专利标题: AZABICYCLIC COMPOUNDS FOR RELIEVING PAIN AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS
- 专利标题(中): 氮杂双环化合物缓解疼痛和中枢神经系统疾病的治疗
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申请号: EP04795238.7申请日: 2004-10-15
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公开(公告)号: EP1678172B1公开(公告)日: 2009-12-09
- 发明人: BREINING, Scott R. , BHATTI, Balwinder S. , HAWKINS, Gregory D. , MIAO, Lan , MAZUROV, Anatoly , PHILLIPS, Teresa Y. , MILLER, Craig H.
- 申请人: Targacept, Inc.
- 申请人地址: 200 East First Street, Suite 300 Winston-Salem, NC 27101-4165 US
- 专利权人: Targacept, Inc.
- 当前专利权人: Targacept, Inc.
- 当前专利权人地址: 200 East First Street, Suite 300 Winston-Salem, NC 27101-4165 US
- 代理机构: Crowhurst, Charlotte Waveney
- 优先权: US511697P 20031015
- 国际公布: WO2005037832 20050428
- 主分类号: C07D471/00
- IPC分类号: C07D471/00
摘要:
Patients susceptible to or suffering from disorders, such as central nervous system disorders, which are characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia), are treated by administering a compound of Formulas (1 or 2), as described herein. The compounds of Formulas (1 and 2) are also useful for treating pain, and treating drug addiction, nicotine addiction, and/or obesity. The compounds can exist as individual stereoisomers, racemic mixtures, diastereomers and the like.
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