发明公开
- 专利标题: METHOD OF EVALUATING CANCERIZATION DEGREE
- 专利标题(中): 评估癌症程度的方法
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申请号: EP04773361.3申请日: 2004-09-15
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公开(公告)号: EP1679371A1公开(公告)日: 2006-07-12
- 发明人: USHIJIMA, Toshikazu , HAGIHARA, Atsushi
- 申请人: Sumitomo Chemical Company, Limited , JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER
- 申请人地址: 27-1, Shinkawa 2-chome, Chuo-ku Tokyo 104-8260 JP
- 专利权人: Sumitomo Chemical Company, Limited,JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER
- 当前专利权人: Sumitomo Chemical Company, Limited,JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER
- 当前专利权人地址: 27-1, Shinkawa 2-chome, Chuo-ku Tokyo 104-8260 JP
- 代理机构: Duckworth, Timothy John
- 优先权: JP2003322823 20030916
- 国际公布: WO2005026353 20050324
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; C12Q1/68 ; C12Q1/02 ; A61K45/00 ; A61K48/00 ; A61P35/00 ; A61P43/00 ; G01N33/15 ; G01N33/50
摘要:
The present invention relates to a method for assessing a cancerous state of a mammal-derived specimen, which comprises:
(1) a first step of measuring a methylation frequency of Neurofilament3 gene contained in a mammal-derived specimen or an index value having the correlation therewith, and
(2) a second step of determining a cancerous state of the specimen based on a difference obtained by comparing the measured methylation frequency or the index value having the correlation therewith, with a control; and the like.
(1) a first step of measuring a methylation frequency of Neurofilament3 gene contained in a mammal-derived specimen or an index value having the correlation therewith, and
(2) a second step of determining a cancerous state of the specimen based on a difference obtained by comparing the measured methylation frequency or the index value having the correlation therewith, with a control; and the like.
公开/授权文献
- EP1679371B8 METHOD OF EVALUATING CANCERIZATION DEGREE 公开/授权日:2012-10-24
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