发明公开
EP1681556A1 Imaging fluorescence signals using telecentricity
有权
Fluoreszenzabbildung mittelsTelezentrizität
- 专利标题： Imaging fluorescence signals using telecentricity
- 专利标题（中）： Fluoreszenzabbildung mittelsTelezentrizität
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申请号： EP05000863.0申请日： 2005-01-18
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公开(公告)号： EP1681556A1公开(公告)日： 2006-07-19
- 发明人: Gutekunst, Martin , Guse, Frank , Heckmann, Hans-Georg , Hessling, Martin , Koenig, Joachim
- 申请人： Roche Diagnostics GmbH , F.HOFFMANN-LA ROCHE AG
- 申请人地址： Sandhofer Strasse 116 68305 Mannheim DE
- 专利权人： Roche Diagnostics GmbH,F.HOFFMANN-LA ROCHE AG
- 当前专利权人： Roche Diagnostics GmbH,F.HOFFMANN-LA ROCHE AG
- 当前专利权人地址： Sandhofer Strasse 116 68305 Mannheim DE
- 主分类号： G01N21/64
- IPC分类号： G01N21/64
摘要：
The present invention relates to the field of DNA analysis. In particular, the present invention is directed to a device for the parallel imaging of fluorescence intensities at a plurality of sites as a measure for DNA hybridization. More particular, the present invention is directed to a device to image multiplex real time PCR or to read out DNA microarrays.
According to a preferred embodiment the device comprises holding means (1) for holding a planar support (2) with an assembly of multiple individual sites (3); at least one light source (4) for emitting light comprising at least one excitation frequency; a transducer (5) for receiving fluorescence signals from said sites; a field lens (6); an excitation lens arrangement (10), and an imaging lens arrangement (11), wherein said excitation light path and said fluorescence imaging light path are telecentric on the object side of said field lens and wherein the angle of incidence of the excitation light with said planar support is larger than 0°.
According to a preferred embodiment the device comprises holding means (1) for holding a planar support (2) with an assembly of multiple individual sites (3); at least one light source (4) for emitting light comprising at least one excitation frequency; a transducer (5) for receiving fluorescence signals from said sites; a field lens (6); an excitation lens arrangement (10), and an imaging lens arrangement (11), wherein said excitation light path and said fluorescence imaging light path are telecentric on the object side of said field lens and wherein the angle of incidence of the excitation light with said planar support is larger than 0°.
公开/授权文献
- EP1681556B1 Imaging fluorescence signals using telecentricity 公开/授权日：2007-04-11
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