发明公开
EP1682551A2 BICYCLIC PYRAZOLONE CYTOKINE INHIBITORS
审中-公开
BICYCLISCHE PYRAZOLONE ALS CYTOKININHIBITOREN
- 专利标题： BICYCLIC PYRAZOLONE CYTOKINE INHIBITORS
- 专利标题（中）： BICYCLISCHE PYRAZOLONE ALS CYTOKININHIBITOREN
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申请号： EP04810572.0申请日： 2004-11-09
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公开(公告)号： EP1682551A2公开(公告)日： 2006-07-26
- 发明人: CLARK, Michael, Philip , LAUGHLIN, Steven, Karl , GOLEBIOWSKI, Adam , BRUGEL, Todd, Andrew , SABAT, Mark
- 申请人： THE PROCTER & GAMBLE COMPANY
- 申请人地址： One Procter & Gamble Plaza Cincinnati, Ohio 45202 US
- 专利权人： THE PROCTER & GAMBLE COMPANY
- 当前专利权人： THE PROCTER & GAMBLE COMPANY
- 当前专利权人地址： One Procter & Gamble Plaza Cincinnati, Ohio 45202 US
- 代理机构： Clemo, Nicholas Graham
- 优先权： US518886P 20031110
- 国际公布： WO2005047287 20050526
- 主分类号： C07D487/00
- IPC分类号： C07D487/00 ; A61K31/4162 ; A61P29/00
摘要：
The present invention relates to 6,7-dihydro-5H-pyrazolo[1,2a]pyrazol-1-ones which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising said 6,7-dihydro-5H-pyrazolo[1,2a]pyrazol-1-ones and methods for preventing, abating, or otherwise controlling enzymes which are understood to be the active components responsible for the herein described disease states.
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