发明授权
- 专利标题： PROTEINS INVOLVED IN SIGNAL TRANSDUCTION
- 专利标题（中）： 参与信号转蛋白
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申请号： EP04798462.0申请日： 2004-11-10
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公开(公告)号： EP1685250B1公开(公告)日： 2009-10-28
- 发明人: ROBINSON, Gary, Kevin , COOK, Hannah
- 申请人： University of Kent
- 申请人地址： The Registry, University of Kent Canterbury, Kent CT2 7NZ GB
- 专利权人： University of Kent
- 当前专利权人： University of Kent
- 当前专利权人地址： The Registry, University of Kent Canterbury, Kent CT2 7NZ GB
- 代理机构： Howard, Paul Nicholas
- 优先权： GB0326194 20031110
- 国际公布： WO2005047514 20050526
- 主分类号： C12N15/82
- IPC分类号： C12N15/82
摘要：
The method relates to a method of modulating quorum sensing in bacteria. Quorum sensing is inhibited using peptide hydrolases. This inhibition is used to prevent biofilm formation or to break down established biofilms and may also be used to downregulate the production of virulence determinants by pathogenic bacteria. The invention also relates to the use of peptide hydrolase inhibitors for the upregulation of quorum sensing in bacteria, resulting in the overproduction of proteins and the use of this system as an expression system.
公开/授权文献
- EP1685250A1 PROTEINS INVOLVED IN SIGNAL TRANSDUCTION 公开/授权日：2006-08-02
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