发明公开
EP1686176A1 Production of antibodies in plants with plus-sense single-stranded viral RNA vectors
审中-公开
Pflanzen mit plus-senseeinzelsträngigenRNA Vektoren的产品vonAntikörpern
- 专利标题: Production of antibodies in plants with plus-sense single-stranded viral RNA vectors
- 专利标题(中): Pflanzen mit plus-senseeinzelsträngigenRNA Vektoren的产品vonAntikörpern
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申请号: EP05001819.1申请日: 2005-01-28
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公开(公告)号: EP1686176A1公开(公告)日: 2006-08-02
- 发明人: Giritch, Anatoli , Marillonnet, Sylvestre , Klimyuk, Victor , Gleba, Yuri
- 申请人: Icon Genetics AG
- 申请人地址: Briennerstrasse 12a 80333 München DE
- 专利权人: Icon Genetics AG
- 当前专利权人: Icon Genetics AG
- 当前专利权人地址: Briennerstrasse 12a 80333 München DE
- 代理机构: Hartz, Nikolai
- 主分类号: C12N15/82
- IPC分类号: C12N15/82 ; C12N15/67 ; C12N15/63
摘要:
Process of producing in a plant, in plant tissue, or in plant cells a hetero-oligomeric protein comprising at least a first and a second protein subunit, said process comprising expressing in plant cells at least said first and said second protein subunit by
(i) providing to said plant, said plant tissue or said plant cells a plus-sense single-stranded RNA viral vector encoding at least said first and said second protein subunit or
(ii) providing to said plant, said plant tissue or said plant cells a first and a second plus-sense single-stranded RNA viral vector, said first viral vector encoding at least said first protein subunit, said second viral vector encoding at least said second protein subunit, whereby at least said first viral vector and said second viral vector are non-competing viral vectors.
(i) providing to said plant, said plant tissue or said plant cells a plus-sense single-stranded RNA viral vector encoding at least said first and said second protein subunit or
(ii) providing to said plant, said plant tissue or said plant cells a first and a second plus-sense single-stranded RNA viral vector, said first viral vector encoding at least said first protein subunit, said second viral vector encoding at least said second protein subunit, whereby at least said first viral vector and said second viral vector are non-competing viral vectors.
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