发明公开
EP1697399A2 A HUMAN CYTOTOXIC T-LYMPHOCYTE EPITOPE AND ITS AGONIST EPITOPE FROM THE NON-VARIABLE NUMBER OF TANDEM REPEAT SEQUENCE OF MUC-1
有权
表位人细胞毒性T淋巴细胞及其AGONISTENEPITOP FROM MUC-1的串联重复序列的非可变NUMBER
- 专利标题: A HUMAN CYTOTOXIC T-LYMPHOCYTE EPITOPE AND ITS AGONIST EPITOPE FROM THE NON-VARIABLE NUMBER OF TANDEM REPEAT SEQUENCE OF MUC-1
- 专利标题(中): 表位人细胞毒性T淋巴细胞及其AGONISTENEPITOP FROM MUC-1的串联重复序列的非可变NUMBER
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申请号: EP04814140.2申请日: 2004-12-10
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公开(公告)号: EP1697399A2公开(公告)日: 2006-09-06
- 发明人: SCHLOM, Jeffrey , TSANG, Kwong-Yok
- 申请人: GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS
- 申请人地址: Washington, DC 20231 US
- 专利权人: GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS
- 当前专利权人: GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS
- 当前专利权人地址: Washington, DC 20231 US
- 代理机构: Davies, Jonathan Mark
- 优先权: US529329P 20031212
- 国际公布: WO2005058937 20050630
- 主分类号: C07K1/00
- IPC分类号: C07K1/00
摘要:
Novel MUC-1 epitopes outside the VNTR region are identified. In addition, the first agonist epitope of MUC-1 is described. The employment of agonist epitopes in peptide, protein and vector-based vaccine may well aid in the development of effective vaccines for a range of human cancers.
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