发明公开
EP1697418A2 ANTI-IL-20 RECEPTOR ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION
审中-公开
抗IL-20受体抗体及其使用炎症结合对象和方法
- 专利标题： ANTI-IL-20 RECEPTOR ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION
- 专利标题（中）： 抗IL-20受体抗体及其使用炎症结合对象和方法
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申请号： EP04811758.4申请日： 2004-11-19
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公开(公告)号： EP1697418A2公开(公告)日： 2006-09-06
- 发明人: XU, Wenfeng , KINDSVOGEL, Wayne, R. , CHEN, Zhi , HUGHES, Steven, D. , CHANDRASEKHER, Yasmin, A. , DILLON, Stacey, R. , LEHNER, Joyce, M. , SIADAK, Anthony, W. , SIVAKUMAR, Pallavur, V. , MOORE, Margaret, D.
- 申请人： ZymoGenetics, Inc.
- 申请人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 当前专利权人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 代理机构： MacLean, Martin Robert
- 优先权： US524131P 20031121; US555857P 20040324
- 国际公布： WO2005052001 20050609
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; A61K38/20
摘要：
The present invention relates to blocking the activity of IL-20 receptor polypeptide molecules. IL-20 is a cytokine that is involved in inflammatory processes and human disease. IL-20RA/IL-20RB is a common receptor for IL-20. The present invention includes anti-IL-20 receptor antibodies and binding partners, including anti-IL-20RA, anti-IL-20RB and anti-IL-20RA/IL-20RB antibodies as well as methods for antagonizing IL-20RA and IL-20RB, either individually or together, using such antibodies and binding partners.
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