发明公开
- 专利标题： Deazapurines and uses thereof
- 专利标题（中）： Deazapurine und ihre Verwendung
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申请号： EP06005483.0申请日： 2003-01-07
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公开(公告)号： EP1707566A1公开(公告)日： 2006-10-04
- 发明人: Daun, Jane , Davis, Heather A. , Gusovsky, Fabian , Hishinuma, Ieharu , Jiang, Yimin , Kaneko, Toshihiko , Kikuchi, Kouichi , Kobayashi, Seiichi , Lescarbeau, Andre , Li, Xiang-Yi , Muramoto, Kenzo , Ohi, Norihito , Pesant, Marc , Seletsky, Boris M. , Soejima, Motohiro , Yao, Ye , Yokohama, Hiromitsu , Zhao, Yan J. , Zheng, Wanjun , Tremblay, Lynda , DeCosta, Bruce F. , Spyvee, Mark
- 申请人： Eisai Co., Ltd.
- 申请人地址： 6-10, Koishikawa 4-chome, Bunkyo-ku Tokyo 112-8088 JP
- 专利权人： Eisai Co., Ltd.
- 当前专利权人： Eisai Co., Ltd.
- 当前专利权人地址： 6-10, Koishikawa 4-chome, Bunkyo-ku Tokyo 112-8088 JP
- 代理机构： Crooks, Elizabeth Caroline
- 优先权： US346598P 20020107
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437 ; A61P31/12 ; A61P35/00 ; A61P37/00 ; A61P29/00
摘要：
The present invention provides compounds having formula (I), wherein R 1 , R 2 , R 3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.
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