发明公开
EP1751113A1 UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS
有权
FOR P2Y1受体的痛苦血栓SUITABLE尿素拮抗剂治疗
- 专利标题: UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS
- 专利标题(中): FOR P2Y1受体的痛苦血栓SUITABLE尿素拮抗剂治疗
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申请号: EP05747470.2申请日: 2005-05-11
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公开(公告)号: EP1751113A1公开(公告)日: 2007-02-14
- 发明人: CHAO, Hannguang J. , TUERDI, Huji , HERPIN, Timothy , ROBERGE, Jacques Yves , LIU, Yalei , LAWRENCE, R. Michael , REHFUSS, Robert P. , CLARK, Charles G. , QIAO, Jennifer X. , GUNGOR, Timur , LAM, Patrick Y.S. , WANG, Tammy C. , RUEL, Rejean , L'HEUREUX, Alexandre L. , THIBEAULT, Carl , BOUTHILLIER, Gilles , SCHNUR, Dora M.
- 申请人: Bristol-Myers Squibb Pharma Company
- 申请人地址: P.O. Box 4000, Route 206 & Provinceline Road Princeton, New Jersey 08543-4000 US
- 专利权人: Bristol-Myers Squibb Pharma Company
- 当前专利权人: Bristol-Myers Squibb Pharma Company
- 当前专利权人地址: P.O. Box 4000, Route 206 & Provinceline Road Princeton, New Jersey 08543-4000 US
- 代理机构: Beacham, Annabel Rose
- 优先权: US570288P 20040512; US665817P 20050328
- 国际公布: WO2005113511 20051201
- 主分类号: C07D231/50
- IPC分类号: C07D231/50 ; C07D231/40 ; C07D213/40 ; C07D413/12 ; C07D401/12 ; C07D405/12 ; C07D417/12 ; C07D333/36 ; A61K31/444 ; A61P7/02
摘要:
The present invention provides novel pyridyl or phenyl ureas and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating diseases responsive to modulation of P2Y1 receptor activity.
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