发明公开
- 专利标题： PHENYL DERIVATIVES COMPRISING AN ACETYLENE GROUP
- 专利标题（中）： 乙炔含苯基衍生物
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申请号： EP05754803.4申请日： 2005-06-21
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公开(公告)号： EP1765760A1公开(公告)日： 2007-03-28
- 发明人: ACKERMANN, Jean , BINGGELI, Alfred , GRETHER, Uwe , KUHN, Bernd , MAERKI, Hans-Peter , MEYER, Markus , AEBI, Johannes
- 申请人： F.HOFFMANN-LA ROCHE AG
- 申请人地址： Grenzacherstrasse 124 4070 Basel CH
- 专利权人： F.HOFFMANN-LA ROCHE AG
- 当前专利权人： F.HOFFMANN-LA ROCHE AG
- 当前专利权人地址： Grenzacherstrasse 124 4070 Basel CH
- 代理机构： Klostermeyer, Dörte
- 优先权： EP04103116 20040701; EP05101986 20050314
- 国际公布： WO2006002802 20060112
- 主分类号： C07C59/68
- IPC分类号： C07C59/68 ; C07C59/70 ; C07D213/30 ; C07D239/26 ; C07C323/20 ; C07C69/736 ; A61P3/10 ; A61K31/192 ; C07C235/34
摘要：
This invention is concerned with compounds of the formula (I) wherein one of R5, R6 and R7 is formula (II) and X1, X2, R1 to R12, m, n and o are as defined in the description, and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.
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