发明公开
EP1771416A1 A NOVEL POLYMORPH OF (1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANONE)-2-YL] METHYL PIPERIDINE HYDROCHLORIDE (DONEPEZIL HYDROCHLORIDE) AND A PROCESS FOR PRODUCING THEREOF
审中-公开
[（5,6-二甲氧基-1-茚满酮）-2-基]甲基（多奈哌齐盐酸盐）及其制造方法 - 的（1-苄基-4- NEW多晶型物
- 专利标题： A NOVEL POLYMORPH OF (1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANONE)-2-YL] METHYL PIPERIDINE HYDROCHLORIDE (DONEPEZIL HYDROCHLORIDE) AND A PROCESS FOR PRODUCING THEREOF
- 专利标题（中）： [（5,6-二甲氧基-1-茚满酮）-2-基]甲基（多奈哌齐盐酸盐）及其制造方法 - 的（1-苄基-4- NEW多晶型物
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申请号： EP04806738.3申请日： 2004-07-28
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公开(公告)号： EP1771416A1公开(公告)日： 2007-04-11
- 发明人: TARUR, Venkatasubramanian Radhakrishnan , SATHE, Dhananjay Govind , NAIDU, Avinash Venkataraman , AHER, Umesh Parashram , SAWANT, Kamlesh Digambar
- 申请人： USV Limited
- 申请人地址： BSD Marg., Station Road, Govandi Mumbai 400088, Maharashtra IN
- 专利权人： USV Limited
- 当前专利权人： USV Limited
- 当前专利权人地址： BSD Marg., Station Road, Govandi Mumbai 400088, Maharashtra IN
- 代理机构： Henkel, Feiler & Hänzel
- 国际公布： WO2006011154 20060202
- 主分类号： C07D211/32
- IPC分类号： C07D211/32 ; A61K31/445 ; A61P25/28
摘要：
The present invention discloses a novel, stable polymorph of 1-benzyl-4-[(5,6 dimethoxy-l-indanone)-2-y1] methyl piperidine hydrochloride commonly known as Donepezil hydrochloride. Further the present invention discloses a process for producing Donepezil HCl amorphous and it's polymorph Form (VI).
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