发明公开
EP1778652A2 COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS
审中-公开
组合物和方法与PROTEINASEAKTIVIERTEN受体拮抗剂
- 专利标题： COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS
- 专利标题（中）： 组合物和方法与PROTEINASEAKTIVIERTEN受体拮抗剂
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申请号： EP05791547.2申请日： 2005-08-19
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公开(公告)号： EP1778652A2公开(公告)日： 2007-05-02
- 发明人: AGOSTON, Gregory, E. , HEMBROUGH, Todd, A. , LAVALLEE, Theresa, M. , SHAH, Jamshed, H. , SUWANDI, Lita , TRESTON, Anthony, M.
- 申请人： EntreMed, Inc.
- 申请人地址： 9640 Medical Center Drive Rockville, MD 20850 US
- 专利权人： EntreMed, Inc.
- 当前专利权人： EntreMed, Inc.
- 当前专利权人地址： 9640 Medical Center Drive Rockville, MD 20850 US
- 代理机构： Stevens, Ian Edward
- 优先权： US603307P 20040820; US644710P 20050118
- 国际公布： WO2006023844 20060302
- 主分类号： C07D261/18
- IPC分类号： C07D261/18 ; C07D235/30 ; C07D403/02
摘要：
Compositions and methods comprising proteinase activated receptor antagonists are provided. More particularly, the present invention relates to the use of proteins, peptides and molecules that bind to proteinase activated receptor 2, and inhibit the processes associated with the activation of that receptor. More specifically, the present invention provides novel compositions and methods for the treatment of disorders and diseases such as those associated with abnormal cellular proliferation, angiogenesis, inflammation and cancer.
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