发明公开
- 专利标题: RNAI MODULATION OF APOB AND USES THEREOF
- 专利标题(中): APOB的RNAi调制及其用途
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申请号: EP05802154.4申请日: 2005-09-26
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公开(公告)号: EP1802644A2公开(公告)日: 2007-07-04
- 发明人: SOUTSCHEK, Juergen , VORNLOCHER, Hans-Peter , HADWIGER, Philipp , ELBASHIR, Sayda
- 申请人: Alnylam Pharmaceuticals Inc.
- 申请人地址: 300 Third Street Cambridge, MA 02142 US
- 专利权人: Alnylam Pharmaceuticals Inc.
- 当前专利权人: Alnylam Pharmaceuticals Inc.
- 当前专利权人地址: 300 Third Street Cambridge, MA 02142 US
- 代理机构: Ehnis, Tobias
- 优先权: US613141P 20040924
- 国际公布: WO2006036916 20060406
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; A61K31/70 ; C12N5/00
摘要:
The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides.
公开/授权文献
- EP1802644B1 RNAI MODULATION OF APOB AND USES THEREOF 公开/授权日:2012-11-07
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