- 专利标题: ACYLIERTE NONADEPSIPEPTIDE ALS LYSOBACTINDERIVATE
- 专利标题(英): Acylated nonadepsipeptides used as lysobactin derivatives
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申请号: EP05798234.0申请日: 2005-10-22
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公开(公告)号: EP1807443A1公开(公告)日: 2007-07-18
- 发明人: VON NUSSBAUM, Franz , BRUNNER, Nina , ENDERMANN, Rainer , FÜRSTNER, Chantal , HARTMANN, Elke , PAULSEN, Holger , RAGOT, Jacques , SCHIFFER, Guido , SCHUHMACHER, Joachim , SVENSTRUP, Niels , TELSER, Joachim , ANLAUF, Sonja , BRÜNING, Michael-Alexander
- 申请人: AiCuris GmbH & Co. KG
- 申请人地址: Friedrich-Ebert-Strasse 475 42117 Wuppertal DE
- 专利权人: AiCuris GmbH & Co. KG
- 当前专利权人: AiCuris GmbH & Co. KG
- 当前专利权人地址: Friedrich-Ebert-Strasse 475 42117 Wuppertal DE
- 代理机构: Weller, Wolfgang
- 优先权: DE102004053407 20041105
- 国际公布: WO2006048139 20060511
- 主分类号: C07K11/02
- IPC分类号: C07K11/02 ; C07K5/06 ; A61P31/04
摘要:
The invention relates to nonadepsipeptides (lysobactin derivatives), methods for the production thereof, and the use thereof for producing medicaments used for treating and/or preventing diseases, especially bacterial infectious diseases. Said novel lysobactin derivatives distinguish themselves from the natural substance by the N-terminal peptide chain which comprises a 3-(3-pyridyl)-alanyl radical.
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