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公开(公告)号：EP1809654B1
公开(公告)日：2008-10-08
申请号：EP05796321.7
申请日：2005-10-08
发明人： VON NUSSBAUM, Franz , BRUNNER, Nina , ENDERMANN, Rainer , FÜRSTNER, Chantal , HARTMANN, Elke , RAGOT, Jacques , SCHIFFER, Guido , SCHUHMACHER, Joachim , SVENSTRUP, Niels , TELSER, Joachim , ANLAUF, Sonja , BRÜNING, Michael-Alexander
CPC分类号： C07K7/06
摘要： Nonadepsipeptides and processes for preparing the same, as well as their use for producing medicaments for the treatment and/or prophylaxys of diseases, in particular bacterial infectious diseases.
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公开(公告)号：EP1866291A1
公开(公告)日：2007-12-19
申请号：EP06723578.8
申请日：2006-03-21
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , WEIGAND, Stefan , FISCHER, Karin
IPC分类号： C07D245/04 , A61P31/04 , C07K5/06 , C07K5/08 , C07K5/10
CPC分类号： C07K5/0202 , C07D245/04 , C07K5/0812 , C07K5/1016 , C07K7/02 , C07K7/06
摘要： The invention concerns antibacterial amide macrocycles , methods for producing same, their use for treating and/or preventing diseases, as well as their use for producing drugs for treating and/or preventing diseases, in particular bacterial infections.
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公开(公告)号：EP1805212A1
公开(公告)日：2007-07-11
申请号：EP05797316.6
申请日：2005-10-08
发明人： VON NUSSBAUM, Franz , BRUNNER, Nina , ENDERMANN, Rainer , FÜRSTNER, Chantal , HARTMANN, Elke , RAGOT, Jacques , SCHIFFER, Guido , SCHUHMACHER, Joachim , SVENSTRUP, Niels , TELSER, Joachim , ANLAUF, Sonja , BRÜNING, Michael-Alexander
IPC分类号： C07K11/02
摘要： The invention relates to nonadepsipeptides, methods for the production thereof, and the use thereof of producing medicaments used for the treatment and/or prevention of diseases, particularly bacterial infectious diseases.
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公开(公告)号：EP2007794B1
公开(公告)日：2011-09-14
申请号：EP07724241.0
申请日：2007-04-13
发明人： VON NUSSBAUM, Franz , BECK, Hartmut , BRUNNER, Nina , ENDERMANN, Rainer , KOEBBERLING, Johannes , RAGOT, Jacques , TELSER, Joachim , SCHUHMACHER, Joachim , ANLAUF, Sonja , CANCHO-GRANDE, Yolanda , GRESCHAT, Susanne , MILITZER, Hans-Christian , SCHIFFER, Guido
摘要： The invention relates to lysobactin amides, methods for the production thereof, and the use thereof for producing medicaments utilized for treating and/or preventing diseases, particularly bacterial infectious diseases.
摘要翻译： 本发明涉及溶杆菌素酰胺，其制备方法及其用于生产用于治疗和/或预防疾病，特别是细菌感染性疾病的药物的用途。
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公开(公告)号：EP1866291B1
公开(公告)日：2009-07-15
申请号：EP06723578.8
申请日：2006-03-21
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , WEIGAND, Stefan , FISCHER, Karin
IPC分类号： C07D245/04 , A61P31/04 , C07K5/06 , C07K5/08 , C07K5/10
CPC分类号： C07K5/0202 , C07D245/04 , C07K5/0812 , C07K5/1016 , C07K7/02 , C07K7/06
摘要： The invention concerns antibacterial amide macrocycles , methods for producing same, their use for treating and/or preventing diseases, as well as their use for producing drugs for treating and/or preventing diseases, in particular bacterial infections.
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公开(公告)号：EP1869068A1
公开(公告)日：2007-12-26
申请号：EP06723614.1
申请日：2006-03-22
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , WEIGAND, Stefan , FISCHER, Karin
CPC分类号： C07K5/0812 , C07K5/02 , C07K5/1016 , C07K7/02
摘要： The invention relates to antibacterial amide-macrocycles of formula (I), in which R26 represents hydrogen, halogen, amino or methyl, R7 represents a group of formula (II), (III), (IV) or (V), where R1 represents hydrogen or hydroxy and * stands for the bonding point on the carbon atom, and R2 represents hydrogen or methyl. The invention also relates to a method for producing said macrocycles, to their use for the treatment and/or prophylaxis of diseases and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
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公开(公告)号：EP1809657A1
公开(公告)日：2007-07-25
申请号：EP05798236.5
申请日：2005-10-26
发明人： VON NUSSBAUM, Franz , BRUNNER, Nina , FÜRSTNER, Chantal , ENDERMANN, Rainer , RAGOT, Jacques , TELSER, Joachim , SCHRÖDER, Werner , ANLAUF, Sonja , SCHUHMACHER, Joachim , HARTMANN, Elke
CPC分类号： C07K7/56
摘要： The invention relates to cyclic nonapeptide amides, methods for the production thereof, and the use thereof for producing medicaments used for treating and/or preventing diseases, especially bacterial infectious diseases.
摘要翻译： 本发明涉及环状九肽酰胺，其制备方法及其用于制备用于治疗和/或预防疾病，特别是细菌感染性疾病的药物的用途。
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公开(公告)号：EP1809653A1
公开(公告)日：2007-07-25
申请号：EP05790976.4
申请日：2005-10-08
发明人： VON NUSSBAUM, Franz , BRUNNER, Nina , ENDERMANN, Rainer , FÜRSTNER, Chantal , HARTMANN, Elke , RAGOT, Jacques , SCHIFFER, Guido , SCHUHMACHER, Joachim , SVENSTRUP, Niels , TELSER, Joachim , ANLAUF, Sonja , BRÜNING, Michael-Alexander
CPC分类号： C07K7/06
摘要： The invention relates to nonadepsipeptides and methods for production as well as use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular, bacterial infective diseases.
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公开(公告)号：EP1797110A1
公开(公告)日：2007-06-20
申请号：EP05782906.1
申请日：2005-09-15
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , FREIBERG, Christoph , RADDATZ, Siegfried , MICHELS, Martin , CANCHO-GRANDE, Yolanda , SCHUHMACHER, Joachim , WEIGAND, Stefan
CPC分类号： C07K7/06 , A61K38/00 , C07K5/0812 , C07K5/1016 , Y02A50/475 , Y02A50/481
摘要： The invention relates to antibacterial amide macrocycles and to a method for the production thereof, to the use thereof in the treatment and/or prophylaxis of diseases, and to the use thereof in the production of medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
摘要翻译： 本发明涉及抗菌酰胺大环化合物及其制备方法，其用于治疗和/或预防疾病的用途，及其在制备用于治疗和/或预防疾病， 特别是细菌感染。
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公开(公告)号：EP1697400B1
公开(公告)日：2011-05-25
申请号：EP04801192.8
申请日：2004-12-02
发明人： ENDERMANN, Rainer , EHLERT, Kerstin , RADDATZ, Siegfried , CANCHO GRANDE, Yolanda , MICHELS, Martin , WEIGAND, Stefan , ADELT, Isabelle , LAMPE, Thomas
CPC分类号： C07K7/06 , C07K5/0812 , C07K5/1016
摘要： The invention relates to biphenyl-substituted antibacterial macrocycles, to methods for their production, to their use in the treatment and/or prophylaxis of diseases, in addition to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infections.
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