发明授权
- 专利标题： SYSTÈME DOUBLE-HYBRIDE BASÉ SUR LA MISE SOUS SILENCE DE GÈNES PAR INTERFÉRENCE TRANSCRIPTIONNELLE.
- 专利标题（英）： Double hybrid system based on gene silencing by transcriptional interference
- 专利标题（中）： 基于基因沉默BY转录干扰双杂交系统
-
申请号： EP05812049.4申请日： 2005-10-24
-
公开(公告)号： EP1807697B1公开(公告)日： 2009-10-21
- 发明人: FOURNIER, Alain , BEHRENS, Ralf , BANDIERA, Silvio
- 申请人： Aventis Pharma S.A.
- 申请人地址： 20, avenue Raymond Aron 92160 Antony FR
- 专利权人： Aventis Pharma S.A.
- 当前专利权人： Aventis Pharma S.A.
- 当前专利权人地址： 20, avenue Raymond Aron 92160 Antony FR
- 代理机构： Bouvet, Philippe
- 优先权： FR0411372 20041025
- 国际公布： WO2006045941 20060504
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C12N15/65 ; C12N15/81 ; C12Q1/68
摘要：
The invention relates to a novel double hybrid system and to the uses thereof. This system provides, in particular, a tool that enables the detection of the interruption of a protein-protein interaction. The developed system uses transcription interference as a mechanism for detecting a breaking up of interacting protein pairs. The developed double hybrid system can be applied to the screening of molecules enabling the detection of molecules breaking up a protein-protein interaction as well as enabling the identification of alleles lacking in the interaction of proteins involved in the protein-protein interactions.
公开/授权文献
信息查询
IPC分类:
