发明公开
- 专利标题: METHODS FOR EXPRESSION AND PURIFICATION OF RECOMBINANT HUMAN GROWTH HORMONE
- 专利标题(中): 方法表达和纯化重组人生长激素
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申请号: EP05857169.6申请日: 2005-12-21
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公开(公告)号: EP1836316A2公开(公告)日: 2007-09-26
- 发明人: BUECHLER, Ying , LIEU, Ricky , ONG, Michael , BUSSELL, Stuart , KNUDSEN, Nick , CHO, Ho Sung
- 申请人: Ambrx, Inc.
- 申请人地址: 10975 North Torrey Pines Road, Suite 100 La Jolla CA 92037 US
- 专利权人: Ambrx, Inc.
- 当前专利权人: Ambrx, Inc.
- 当前专利权人地址: 10975 North Torrey Pines Road, Suite 100 La Jolla CA 92037 US
- 代理机构: Mercer, Christopher Paul
- 优先权: US638616P 20041222; US655744P 20050223; US680977P 20050513; US727968P 20051017
- 国际公布: WO2006073846 20060713
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07H21/04 ; C07K14/61 ; A61K38/27
摘要:
The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH from recombinant host cells or culture medium including, for example, yeast, insect, mammalian and bacterial host cells. The process of the present invention is also useful for purification of hGH linked to polymers or other molecules.
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