公开(公告)号：EP1836316A2

公开(公告)日：2007-09-26

申请号：EP05857169.6

申请日：2005-12-21

申请人： Ambrx, Inc.

发明人： BUECHLER, Ying ,  LIEU, Ricky ,  ONG, Michael ,  BUSSELL, Stuart ,  KNUDSEN, Nick ,  CHO, Ho Sung

IPC分类号： C12Q1/68 ,  C07H21/04 ,  C07K14/61 ,  A61K38/27

CPC分类号： C07K14/61

摘要： The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH from recombinant host cells or culture medium including, for example, yeast, insect, mammalian and bacterial host cells. The process of the present invention is also useful for purification of hGH linked to polymers or other molecules.