发明公开
EP1838306A1 NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS
有权
NEW 2-氨基 - 苯并咪唑衍生物和它们作为调制器，具有低的电导率钙激活钾通道
- 专利标题： NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS
- 专利标题（中）： NEW 2-氨基 - 苯并咪唑衍生物和它们作为调制器，具有低的电导率钙激活钾通道
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申请号： EP06701206.2申请日： 2006-01-10
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公开(公告)号： EP1838306A1公开(公告)日： 2007-10-03
- 发明人: SØRENSEN, Ulrik, Svane , TEUBER, Lene , PETERS, Dan , STRØBÆK, Dorte , JOHANSEN, Tina, Holm , NIELSEN, Karin, Sandager , CHRISTOPHERSEN, Palle
- 申请人： NEUROSEARCH A/S
- 申请人地址： Patent Dept., Pederstrupvej 93 2750 Ballerup DK
- 专利权人： NEUROSEARCH A/S
- 当前专利权人： NEUROSEARCH A/S
- 当前专利权人地址： Patent Dept., Pederstrupvej 93 2750 Ballerup DK
- 代理机构： Abildgren, Michael Padkjaer
- 优先权： US642538P 20050111; DK200500049 20050111; DK200500240 20050216; US653513P 20050217
- 国际公布： WO2006074991 20060720
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; C07D235/30 ; A61P25/00
摘要：
This invention relates to novel 2-amino benzimidazole derivatives of formula (I1) and (Ib) useful as modulators of small-conductance calcium-activated potassium channels (SK channels) . In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
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