发明公开
- 专利标题： A PROCESS FOR THE PURIFICATION OF GABAPENTIN
- 专利标题（中）： 法提纯加巴喷丁
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申请号： EP05823475.8申请日： 2005-12-15
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公开(公告)号： EP1841725A1公开(公告)日： 2007-10-10
- 发明人: GIOVANETTI, Roberto , NICOLI, Andrea , COTARCA, Livius
- 申请人： ZaCh System S.p.A.
- 申请人地址： Via Lillo del Duca, 10 20091 Bresso (Milano) IT
- 专利权人： ZaCh System S.p.A.
- 当前专利权人： ZaCh System S.p.A.
- 当前专利权人地址： Via Lillo del Duca, 10 20091 Bresso (Milano) IT
- 优先权： ITMI20042418 20041217
- 国际公布： WO2006064041 20060622
- 主分类号： C07C227/40
- IPC分类号： C07C227/40 ; C07C229/28
摘要：
The present invention relates to a process for the purification of gabapentin. The process relates to the addition of hydrochloric acid to an aqueous solution or suspension of gabapentin, before, during or after the concentration step of that solution, and the subsequent slurry of the gabapentin by the addition of an alcoholic solvent. The so obtained gabapentin has an high purity degree and, in particular, is characterized by a low content of lactam.
公开/授权文献
- EP1841725B1 A PROCESS FOR THE PURIFICATION OF GABAPENTIN 公开/授权日：2009-03-25
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