发明授权
- 专利标题： SYNTHESIS OF HIMBACINE ANALOGS
- 专利标题（中）： 合成HIMBACINANALOGA的
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申请号： EP06718299.8申请日： 2006-01-12
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公开(公告)号： EP1853592B1公开(公告)日： 2011-03-02
- 发明人: THIRUVENGADAM, Tiruvettipuram, K. , WANG, Tao , LIAO, Jing , CHIU, John, S. , TSAI, David, J. S. , LEE, Hong-chang , WU, Wenxue , FU, Xiaoyong
- 申请人： Schering Corporation
- 申请人地址： 2000 Galloping Hill Road Kenilworth, NJ 07033 US
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 当前专利权人地址： 2000 Galloping Hill Road Kenilworth, NJ 07033 US
- 代理机构： Buchan, Gavin MacNicol
- 优先权： US643932P 20050114
- 国际公布： WO2006076564 20060720
- 主分类号： C07D405/08
- IPC分类号： C07D405/08 ; C07D493/10 ; C07D307/88
摘要：
The present invention relates to an improved process for preparing imbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield on the desired enantiomer. An example of a step in the synthesis of such a himbacine analog is as follows: Formula (I)
公开/授权文献
- EP1853592A1 SYNTHESIS OF HIMBACINE ANALOGS 公开/授权日：2007-11-14
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