发明公开
- 专利标题： Soluble interleukin-20 receptor
- 专利标题（中）： 可溶性白介素20受体
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申请号： EP07012370.8申请日： 2000-12-22
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公开(公告)号： EP1857466A3公开(公告)日： 2008-02-13
- 发明人: Foster, Donald C. , Xu, Wenfeng , Madden, Kare L. , Kelly, James D. , Sprecher, Cindy A. , Brandt, Cameron S. , Rixon, Mark W. , Presnell, Scott R. , Fox, Brian A.
- 申请人： ZymoGenetics, Inc.
- 申请人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 当前专利权人地址： 1201 Eastlake Avenue East Seattle, WA 98102 US
- 代理机构： MacLean, Martin Robert
- 优先权： US471774 19991223; US213416P 20000622
- 主分类号： C07K14/715
- IPC分类号： C07K14/715 ; C12N15/62 ; C12N15/09 ; C07K16/00 ; A61P17/06
摘要：
A soluble receptor to IL-20 having two polypeptide subunits, IL-20RA (formerly called ZcytoR7) and IL-20RB (formerly called DIRS1). The two subunits are preferably linked together. In one embodiment one subunit is fused to the constant region of the light chain of an immunoglobulin, and the other subunit is fused to the constant region of the heavy chain of the immunoglobulin. The light chain and the heavy chain are connected via a disulfide bond.
公开/授权文献
- EP1857466B1 Soluble interleukin-20 receptor 公开/授权日：2010-10-20
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