发明公开
EP1859805A2 Peptides and peptide analogues designed from the HFE protein and their uses in the treatment of iron overload diseases
审中-公开
在HFE蛋白开发的肽和肽类似物及其用途的基础铁过剩症的治疗
- 专利标题： Peptides and peptide analogues designed from the HFE protein and their uses in the treatment of iron overload diseases
- 专利标题（中）： 在HFE蛋白开发的肽和肽类似物及其用途的基础铁过剩症的治疗
-
申请号： EP06022921.8申请日： 1999-12-10
-
公开(公告)号： EP1859805A2公开(公告)日： 2007-11-28
- 发明人: Feder, John N. , Schatzman, Randall C. , Bjorkman, Pamela J. , Bennett, Melanie , Lebron, Jose
- 申请人： Bio-Rad Laboratories, Inc. , CALIFORNIA INSTITUTE OF TECHNOLOGY
- 申请人地址： 1000 Alfred Nobel Drive Hercules, CA 94547 US
- 专利权人： Bio-Rad Laboratories, Inc.,CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人： Bio-Rad Laboratories, Inc.,CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人地址： 1000 Alfred Nobel Drive Hercules, CA 94547 US
- 代理机构： Horner, Martin Grenville
- 优先权： US216077 19981218
- 主分类号： A61K38/03
- IPC分类号： A61K38/03 ; A61K38/04 ; A61K38/10 ; C07K7/04 ; C07K7/08
摘要：
The present invention relates to peptides and peptide analogues designed from HFE protein. In particular, it relates to peptides and peptide analogues designed from an alpha-1 region of HFE protein which lowers the binding affinity of transferrin receptor for transferrin. Such compounds mimic HFE protein function, and reduce iron uptake and/or accumulation by a cell.
公开/授权文献
信息查询
IPC分类:
