发明授权
- 专利标题: ANTI-IgSF4 ANTIBODY AND UTILIZATION OF THE SAME
- 专利标题(中): ANTI-IGSF4抗体及其用途
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申请号: EP06714335.4申请日: 2006-02-22
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公开(公告)号: EP1860119B1公开(公告)日: 2011-08-03
- 发明人: AKAHORI, Yasushi , SUGIOKA, Atsushi, VIEQU COURT DENJIYAMA , HAYASHI, Nobuhiro , TAKASAKI, Akihiko , SUZUKI, Kazuhiro , MORITA, Miwa , KUROSAWA, Yoshikazu , IBA, Yoshitaka , SUMITOMO, Mariko , TSUTSUMI, Susumu , OGAWA, Keiko , MATSUDA, Kazuki , MURAMATSU, Chiho , TAKAHASHI, Nobuhiro, c/o The Faculty of Agriculture , FUJIYAMA, Sari , AZUMA, Masachika, c/o Inst. Antibodies Co., Ltd , UKAI, Yoshinori, c/o Inst. Antibodies Co., Ltd , MORISHITA, Kazuhiro, Miyazaki Medical College, Dept. of Biochemistry
- 申请人: Institute for Antibodies Co., Ltd. , Kurosawa, Yoshikazu
- 申请人地址: 4-5-3, Sakae Naka-ku Nagoya Aichi 460-0008 JP
- 专利权人: Institute for Antibodies Co., Ltd.,Kurosawa, Yoshikazu
- 当前专利权人: Institute for Antibodies Co., Ltd.,Kurosawa, Yoshikazu
- 当前专利权人地址: 4-5-3, Sakae Naka-ku Nagoya Aichi 460-0008 JP
- 代理机构: Müller Fottner Steinecke
- 优先权: JP2005054624 20050227
- 国际公布: WO2006090750 20060831
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K39/00 ; A61P35/00 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12N15/09 ; C12Q1/02 ; G01N33/15 ; G01N33/50
摘要:
It is intended to clarify a molecule which is available as a target in treating or diagnosing cancer and utilize the molecule in the medical field or the research field. By treating IgSF4, which has been identified as a molecule specifically expressed in lung cancer cells, with an antibody, an ADCC activity is exerted. Based on this finding, an anti-IgSF4 antibody is provided as a means efficacious in treating cancer, etc.
公开/授权文献
- EP1860119A1 ANTI-IgSF4 ANTIBODY AND UTILIZATION OF THE SAME 公开/授权日:2007-11-28
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