发明公开
EP1861169A2 METHOD AND COMPOSITION FOR TREATING MUCOSAL DISORDERS
有权
的使用13,14-二氢-15-酮基-16,16-二氟E1或13,14-二氢-15-酮基-16,16-二氟-18-甲基前列腺素E1用于治疗癌症的
- 专利标题: METHOD AND COMPOSITION FOR TREATING MUCOSAL DISORDERS
- 专利标题(中): 的使用13,14-二氢-15-酮基-16,16-二氟E1或13,14-二氢-15-酮基-16,16-二氟-18-甲基前列腺素E1用于治疗癌症的
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申请号: EP06730328.9申请日: 2006-03-22
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公开(公告)号: EP1861169A2公开(公告)日: 2007-12-05
- 发明人: UENO, Ryuji , KUNO, Sachiko , BLIKSLAGER, Anthony, T. , MOESER, Adam, J.
- 申请人: Sucampo AG , NORTH CAROLINA STATE UNIVERSITY
- 申请人地址: Graben 5 6300 Zug CH
- 专利权人: Sucampo AG,NORTH CAROLINA STATE UNIVERSITY
- 当前专利权人: Sucampo AG,NORTH CAROLINA STATE UNIVERSITY
- 当前专利权人地址: Graben 5 6300 Zug CH
- 代理机构: Albrecht, Thomas
- 优先权: US663200P 20050321; US679920P 20050511; US721976P 20050930
- 国际公布: WO2006101244 20060928
- 主分类号: A61P1/04
- IPC分类号: A61P1/04 ; A61P35/00 ; A61K31/557 ; C07C405/00
摘要:
Provided is a method and composition for treating mucosal disorders using a specific prostaglandin compound. The prostaglandin compound induces a conformational change in the tight junction that results in recovery of mucosal barrier function. Accordingly, the prostaglandin compound used herein is useful for the treatment of mucosal disorders.
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