发明公开
EP1868615A2 MODULATION OF TELOMERE LENGTH IN TELOMERASE POSITIVE CELLS AND CANCER THERAPY 审中-公开
TELOMERLÄNGENMODULATION端粒酶阳性细胞和癌症治疗

  • 专利标题: MODULATION OF TELOMERE LENGTH IN TELOMERASE POSITIVE CELLS AND CANCER THERAPY
  • 专利标题(中): TELOMERLÄNGENMODULATION端粒酶阳性细胞和癌症治疗
  • 申请号: EP06748718.1
    申请日: 2006-03-27
  • 公开(公告)号: EP1868615A2
    公开(公告)日: 2007-12-26
  • 发明人: BONDAREV, Igor, E.
  • 申请人: Alt Solutions, Inc.
  • 申请人地址: Corporation Trust Center 1209 Orange Street Wilmington, DE 19801 US
  • 专利权人: Alt Solutions, Inc.
  • 当前专利权人: Alt Solutions, Inc.
  • 当前专利权人地址: Corporation Trust Center 1209 Orange Street Wilmington, DE 19801 US
  • 代理机构: Vossius & Partner
  • 优先权: US665105P 20050325
  • 国际公布: WO2006104975 20061005
  • 主分类号: A61K31/675
  • IPC分类号: A61K31/675
MODULATION OF TELOMERE LENGTH IN TELOMERASE POSITIVE CELLS AND CANCER THERAPY
摘要:
Induction of telomere shortening, G2 arrest and apoptosis in telomerase positive cancer cells using acyclic nucleoside analogs has been disclosed. In addition, methods for impairment or prevention of tumorigenic telomerase positive cells from having a chance to grow into a tumor and methods for promoting tumor regression (decrease in size of an established tumor) using acyclic nucleoside analogs has been disclosed.
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