发明公开
EP1879891A1 MUTUAL PRODRUG COMPOUNDS FOR USE AS ANTIINFLAMMATORY AGENTS WITH GASTROINTESTINAL PROTECTIVE ACTIVITY
审中-公开
常见的前药化合物用作具有胃肠道保护作用抗炎剂
- 专利标题： MUTUAL PRODRUG COMPOUNDS FOR USE AS ANTIINFLAMMATORY AGENTS WITH GASTROINTESTINAL PROTECTIVE ACTIVITY
- 专利标题（中）： 常见的前药化合物用作具有胃肠道保护作用抗炎剂
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申请号： EP06754865.1申请日： 2006-04-26
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公开(公告)号： EP1879891A1公开(公告)日： 2008-01-23
- 发明人: BREHM, Christof , KLEIN, Thomas , BUHR, Wilm , CHIESA, Maria, Vittoria , PALMER, Andreas , ZIMMERMANN, Peter, Jan , SIMON, Wolfgang-Alexander , KROMER, Wolfgang , POSTIUS, Stefan , GRUNDLER, Gerhard
- 申请人： Nycomed GmbH
- 申请人地址： Byk-Gulden-Strasse 2 78467 Konstanz DE
- 专利权人： Nycomed GmbH
- 当前专利权人： Nycomed GmbH
- 当前专利权人地址： Byk-Gulden-Strasse 2 78467 Konstanz DE
- 代理机构： Neels, Solvig
- 优先权： EP05103581 20050429
- 国际公布： WO2006117315 20061109
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/4188 ; A61P29/00 ; A61P1/04
摘要：
The invention relates compounds of the formula I, in which the substituents and symbols have the meanings as indicated in the description. The compounds are prodrugs and exhibit in the human and/or animal body antipyretic, analgesic, antiphlogistic and/or anti-inflammatory activity as well as gastric acid secretion inhibiting and therefore gastro and intestinal protective activity. Formula (I)
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