发明公开
EP1881987A1 PURINE DERIVATIVES AND THEIR USE FOR TREATMENT OF AUTOIMMUNE DISEASES
有权
嘌呤衍生物和它们用于自身免疫性疾病的治疗
- 专利标题： PURINE DERIVATIVES AND THEIR USE FOR TREATMENT OF AUTOIMMUNE DISEASES
- 专利标题（中）： 嘌呤衍生物和它们用于自身免疫性疾病的治疗
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申请号： EP06790516.6申请日： 2006-05-15
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公开(公告)号： EP1881987A1公开(公告)日： 2008-01-30
- 发明人: ZACHARIE, Boulos , FORTIN, Daniel , WILB, Nicole , PENNEY, Christopher
- 申请人： ProMetic BioSciences Inc.
- 申请人地址： 8168 Montview Mont-Royal Québec H4P 2L7 CA
- 专利权人： ProMetic BioSciences Inc.
- 当前专利权人： ProMetic BioSciences Inc.
- 当前专利权人地址： 8168 Montview Mont-Royal Québec H4P 2L7 CA
- 代理机构： McCluskie, Gail Wilson
- 优先权： US681141P 20050516
- 国际公布： WO2006136005 20061228
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/52
摘要：
Compounds useful in the treatment of autoimmune disease are described by the following general formula (I): n = 0-2 m = 0-2 m is not necessarily equal to n; where R1, R3 = NH2, F, Cl, C1-C4 alkoxy or phenoxy group, but R1 is not necessarily equal to R3; and R2 = H, F, Cl, NH2, or NH- R- XH; where R = - (CH2)p - p = 2-4 = Formula (II), Formula (III) = Formula (IV) q = 0-3 X = CH2, NH, O, or S.
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