发明公开
- 专利标题: Method for detecting a methylation pattern
- 专利标题(中): 检测甲基化模式的方法
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申请号: EP07111614.9申请日: 2007-07-12
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公开(公告)号: EP1882746A2公开(公告)日: 2008-01-30
- 发明人: Berlin, Kurt , Distler, Jürgen , Tetzner, Reimo
- 申请人: Epigenomics AG
- 申请人地址: Intellectual Property Kleine Präsidentenstrasse 1 10178 Berlin DE
- 专利权人: Epigenomics AG
- 当前专利权人: Epigenomics AG
- 当前专利权人地址: Intellectual Property Kleine Präsidentenstrasse 1 10178 Berlin DE
- 优先权: EP06076487 20060727
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The present invention relates to a method for detecting the presence of one or more methylation patterns. It comprises the conversion of nucleic acids and a catalytic nucleic acid activity. Here, the conversion of the nucleic acid is characterized such that the 5-methylcytosine remains unchanged while the unmethylated cytosine is converted into uracil or another base, which can be distinguished from cytosine in its base-pairing behavior.
公开/授权文献
- EP1882746A3 Method for detecting a methylation pattern 公开/授权日:2008-03-19
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