发明公开
EP1888586A2 2,3-SUBSTITUTED FUSED BICYCLIC PYRIMIDIN-4(3H)-ONES WHICH MODULATE THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1)
审中-公开
2,3-取代的嘧啶稠合双环嘧啶-4（3H） - 酮，香草素-1受体的功能（VR1）MODULATE
- 专利标题： 2,3-SUBSTITUTED FUSED BICYCLIC PYRIMIDIN-4(3H)-ONES WHICH MODULATE THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1)
- 专利标题（中）： 2,3-取代的嘧啶稠合双环嘧啶-4（3H） - 酮，香草素-1受体的功能（VR1）MODULATE
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申请号： EP06727195.7申请日： 2006-05-10
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公开(公告)号： EP1888586A2公开(公告)日： 2008-02-20
- 发明人: BAYLISS, Tracy , BROWN, Rebecca Elizabeth , HOLLINGWORTH, Gregory John , JONES, A. Brian
- 申请人： MERCK SHARP & DOHME LTD.
- 申请人地址： Hertford Road Hoddesdon, Hertfordshire EN11 9BU GB
- 专利权人： MERCK SHARP & DOHME LTD.
- 当前专利权人： MERCK SHARP & DOHME LTD.
- 当前专利权人地址： Hertford Road Hoddesdon, Hertfordshire EN11 9BU GB
- 代理机构： Horgan, James Michael Frederic
- 优先权： GB0509573 20050511
- 国际公布： WO2006120481 20061116
- 主分类号： C07D473/04
- IPC分类号： C07D473/04 ; A61K31/52 ; A61P25/04 ; A61P29/00
摘要：
Compounds of formula (I) which are useful as therapeutic compounds, particularly in the treatment of pain and other conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VRl, also known as TRPVl).
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