发明公开
- 专利标题： ANTINEOPLASTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF
- 专利标题（中）： 抗生素治疗药物佐治美
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申请号： EP06753157.4申请日： 2006-05-05
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公开(公告)号： EP1892245A2公开(公告)日： 2008-02-27
- 发明人: RODRIGUEZ FERNANDEZ, Rolando Eduardo , VERA ALVAREZ, Roberto , DE LA NUEZ VEULENS, Ania , MAZOLA REYES, Yuliet , PEREA RODRÍGUEZ, Silvio, Ernesto , ACEVEDO CASTRO, Boris Ernesto , MUSACCHIO LASA, Alexis , UBIETA GÓMEZ, Raimundo
- 申请人： CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA
- 申请人地址： Ave. 31 entre 158 y 190 Cubanacan, Playa Ciudad de La Habana 10600 CU
- 专利权人： CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA
- 当前专利权人： CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA
- 当前专利权人地址： Ave. 31 entre 158 y 190 Cubanacan, Playa Ciudad de La Habana 10600 CU
- 代理机构： Hatzmann, Martin
- 优先权： CU912005 20050512
- 国际公布： WO2006119713 20061116
- 主分类号： C07F9/22
- IPC分类号： C07F9/22 ; C07D487/04 ; C07D239/42 ; C07D239/36 ; C07D233/54 ; C07D235/14 ; C07D215/18 ; C07D213/82 ; C07D207/36 ; C07C237/30 ; C07C327/44 ; C07C313/06 ; C07C275/36 ; C07C275/22 ; C07C275/18
摘要：
Chemical compounds identified by in silico molecular modelling, and having an structure that allows the blocking of the phosphorylation event, through the interaction of such compounds with the phosphorylation domain or its milieu in the substrates of the Casein Kinase 2 enzyme. This invention comprises also the pharmaceutical compositions containing such compounds, and their use in the preparation of medicines for the treatment of diseases related with neoplasic processes.
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